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The synthesis of 7-carbonyl homologues of 1-deoxynojirimycin

✍ Scribed by Amuri Kilonda; Frans Compernolle; Suzanne Toppet; Georges J. Hoornaert


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
311 KB
Volume
35
Category
Article
ISSN
0040-4039

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The synthesis of 2-acetamido-1 ,Zdideoxynojirimycin (Zacetamido-1,2,5-trideoxy-1,5-imino-D-glucitol) by a double inversion procedure starting from l-deoxynojirimycin is reported. The key intermediates were the selectively protected N-benzyl-l,5-dideoxy-l,5-imino-4,6-0-isopropylidene-~-mannitol, the