The Synthesis of 5,5-Alkylphenylbarbituric Acids1,2
β Scribed by Chamberlain, J. S.; Chap, J. J.; Doyle, J. E.; Spaulding, L. B.
- Book ID
- 115458835
- Publisher
- American Chemical Society
- Year
- 1935
- Tongue
- English
- Weight
- 333 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
## Abstract 5β[4,5β^13^C~2~]β and 5β[1,5β^13^C~2~]Aminolevulinic acid (ALA) have been synthesized by the Gabriel condensation of potassium phthalimide with ethyl bromo[1,2β^13^C~2~]acetate (derived from [1,2β^13^C~2~]acetic acid) or ethyl bromo[2β^13^C]βacetate (derived from sodium [2β^13^C]acetate
Carbonylation of 1-undecene with 13C0 under a hydrogen atmosphere with pa 1 ladi um-s tannous ch 1 or ide cata 1 ys t afforded [ 1-13C Idodecanoi c ( 1 aur i c acid on a 0.25 mole scale. Reduction to the alcohol and treatment with concentrated HBr gave 1-[l-C]bromododecane which was used to alkylate