The synthesis of 3,4,4a,9a-tetrahydro-2(1H)-carbazolones
✍ Scribed by Raymond R. Wittekind; Sam Lazarus
- Book ID
- 112122301
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1970
- Tongue
- English
- Weight
- 568 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
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## Abstract (3R)‐3‐(4‐Fluorophenylsulfonamido)‐1, 2, 3, 4‐tetrahydro‐9‐[4‐^3^H]carbazolepropanoic acid ([^3^H]BAY u 3405) (5) was synthesized by catalytic reduction of (3R)‐3‐(4‐fluorophenylsulfon‐amido)‐4‐oxo‐1, 2, 3, 4‐tetrahydro‐9‐carbazolepropanoic acid (4) with tritium. The precursor (4) was p
Two sequential palladium-catalyzed reactions are the key steps in a novel synthetic route to carbazolones, an intermolecular Stille coupling followed by a recently developed palladium-catalyzed reductive N-heteroannulation. A number of functionalized 1,2-dihydro-4(3H)-carbazolones were prepared usin