✦ LIBER ✦

The synthesis of (2R,3R)-3-(L-Aspartylamino)-1-[(2S,3R)-3-methyl-2-norbornyl]-2-butanol, An excellent sweetener

✍ Scribed by Yoshifumi Yuasa; Akira Nagakura; Haruki Tsuruta

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 424 KB
Volume: 11
Category: Article
ISSN: 0882-5734
DOI: 10.1002/(sici)1099-1026(199611)11:6<327::aid-ffj600>3.0.co;2-o

No coin nor oath required. For personal study only.

✦ Synopsis

Some L-aspartylnorbornylamino alcohol derivatives were synthesized as potential peptide sweeteners. Of these compounds, 3-(~-aspartylamino)-l-(3-methyl-2-norbornyl)-2-butanol displays an excellent sweetness potency. By further synthesis of one diastereoisomer, (2R,3R)-3-(~-aspartylamino)-1-[(2S,3R)-3-methyl-2-norbornyl]-2butanol, we obtained an excellent and potent sweetener.

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