Phenols enriched w i t h oxygen-18 can be synthesized u s i n g an a c i d exchange r e a c t i o n i n H2180 a t e l e v a t e d temperature, however, t o o b t a i n h i g h l y enriched products very l a r g e quant i t i e s of water must be used and recycled. Grignard reagents w i l l r e a c t
The synthesis of 18O-enriched KO2
β Scribed by I. Rosenthal
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- French
- Weight
- 90 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0022-2135
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## Abstract 8β[^18^O]Hydroxyβ2β²βdeoxyguanosine was synthesized starting from 8βbromoβ2β²βdeoxyguanosine and the sodium salt of [^18^O]benzyl alcohol, resulting in the intermediate 8β[^18^O]benzyloxyβ2β²βdeoxyguanosine. Subsequent reduction by catalytic transfer hydrogenation, yielded the desired prod
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