The synthesis and transformations of ethyl (Z)-2-[2,2-bis(ethoxycarbonyl)vinyl]amino-3-dimethylaminopropenoate, a new reagent in the synthesis of heterocyclic compounds
✍ Scribed by Gorazd Soršak; Amalija Sinur; Ljubo Golič; Branko Stanovnik
- Book ID
- 112131269
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1995
- Tongue
- English
- Weight
- 464 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0022-152X
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## Abstract Alkyl 2‐(2‐benzoyl‐2‐ethoxycarbonyl‐1‐ethenyl)amino‐3‐dimethylaminopropenoates 4a,b were prepared. They react with __C__‐nucleophiles such a 2‐pyridinylacetonitrile 5 and methyl‐2‐quinolinylacetate 8, cyclohexane‐1,3‐dione 10 and its derivatives 12 and 14, resorcinol derivative 16, 2‐na
## Abstract Alkyl (Z)‐2‐[(__E__)‐2‐ethoxycarbonyl‐2‐(2‐pyridinyl)ethenyl]amino‐3‐dimethylaminopropenoates **7** and **8** were prepared from ethyl 2‐pyridinylacetate (1) in two steps. Substitution of the dimethylamino group with alkyl‐, aryl‐, or heteroarylamines afforded the corresponding β‐alkyl‐