The synthesis and transformation of ethyl 2-(2-acetyl-2-benzoyl-1-ethenyl)amino-3-dimethylaminopropenoate. A new synthesis of 2,3,4-trisubstituted pyrroles
✍ Scribed by Mateja Malešič; Aleš Krbavčič; Amalija Golobič; Ljubo Golič; Branko Stanovnik
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1997
- Tongue
- English
- Weight
- 506 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0022-152X
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## Abstract Alkyl 2‐(2‐benzoyl‐2‐ethoxycarbonyl‐1‐ethenyl)amino‐3‐dimethylaminopropenoates 4a,b were prepared. They react with __C__‐nucleophiles such a 2‐pyridinylacetonitrile 5 and methyl‐2‐quinolinylacetate 8, cyclohexane‐1,3‐dione 10 and its derivatives 12 and 14, resorcinol derivative 16, 2‐na
## Abstract In the reaction of methyl (__E,Z__)‐2‐(2‐benzoyl‐2‐ethoxycarbonyl‐1‐ethenyl)amino‐3‐dimethylaminopro‐penoate (1) with heteroarylhydrazines 2 in ethanol in the presence of catalytic amounts of hydrochloric acid two types of products were formed: methyl 2‐(2‐benzoyl‐2‐ethoxycarbonyl‐1‐eth
## Abstract Transformations of intermediates 4, prepared from methyl 2‐(2,2‐disubstituted‐ethenyl)amino‐3‐dimethylaminopropenoates 2 and sterically hindered heteroarylamines 3, into methyl 1‐heteroaryl‐1__H__‐imidazole‐4‐carboxylates 7 are described.