Attempted Synthesis of a Vinylog of Chlo
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Lewis Nobles, W. ;Burckhalter, J.H.
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Article
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1958
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Elsevier
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Applying essentially the synthetic procedures of Long and Troutman, which led to chloramphenicol, we have attempted to synthesize a vinylog of the antibiotic in order to study the application of the theory of vinylogy to pharmacological results. However, failure to achieve the desired synthesis has