Attempted Synthesis of a Vinylog of Chlo
β
Lewis Nobles, W. ;Burckhalter, J.H.
π
Article
π
1958
π
Elsevier
β 394 KB
Applying essentially the synthetic procedures of Long and Troutman, which led to chloramphenicol, we have attempted to synthesize a vinylog of the antibiotic in order to study the application of the theory of vinylogy to pharmacological results. However, failure to achieve the desired synthesis has