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The synthesis and characterization of new triphenylethylene platinum(II) complexes

✍ Scribed by Gervais Bérubé; Yuehua He; Serge Groleau; Alexandre Séné; Hélène-Marie Thérien; Madeleine Caron

Book ID
108328545
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
291 KB
Volume
262
Category
Article
ISSN
0020-1693

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In our search for a chemotherapeutic agent with a better therapeutic index and selectivity for the treatment of breast cancer, we have synthesized cytotoxic triphenylethylene derivatives. The synthesis of this type of compound is straightforward and efficient. The biological activity of these compou