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The synthesis and characterization of fatty acid salts of chitosan as novel matrices for prolonged intragastric drug delivery

✍ Scribed by Bani-Jaber, Ahmad; Hamdan, Imad; Alkawareek, Mahmoud


Book ID
120220126
Publisher
Springer
Year
2012
Tongue
English
Weight
554 KB
Volume
35
Category
Article
ISSN
0253-6269

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The main aim of this research was to develop and evaluate a multiparticulate system of Ac-poly(amidoamine)(PAMAM)(G4)-chitosan (CS) hydrogels exploiting pH-sensitive and specific biodegradability properties for colon-targeted delivery of 5-aminosalicylic acid (5-ASA). All formulations were evaluated