The Synthesis and Biological Evaluation of Two Analogues of the C-Riboside Showdomycin.
β Scribed by Jens Renner; Irma Kruszelnicki; Beata Adamiak; Anthony C. Willis; Edward Hammond; Stephen Su; Christopher Burns; Edward Trybala; Vito Ferro; Martin G. Banwell
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 13 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
Largazole (1) is a densely functionalized macrocyclic depsipeptide that was isolated from the cyanobacterium Symploca sp.
Bombesin pseudo-peptide analogues containing a hydroxamide function on the C-terminal part of the molecule, e.g. H-D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-NHOBzl 1 and H-D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-NHOH 2 were synthesized. These compounds were tested for their ability to recognize the bombesin recep