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The synthesis and biological activity of tetrahydroquinoline angiotensin II antagonists containing a substituted biphenyltetrazole group

✍ Scribed by Andrew P. Thomas; David A. Roberts; Douglas A. Thomason


Book ID
108476899
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
403 KB
Volume
4
Category
Article
ISSN
0960-894X

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The synthesis and biological properties of a novel class of 7-heterocycle-substituted quinoxalinecarboxylic acids, which bear a substituted phenyl group through a urethane linkage at the C-7 position, are described. One of the synthesized compounds, 15l, which has a 4-carboxyphenyl carbamoyloxymethy