The Synthesis and Acid-catalyzed Cyclization of α-Methylheptenone
✍ Scribed by Meinwald, Jerrold; Yankeelov, John A.
- Book ID
- 127174868
- Publisher
- American Chemical Society
- Year
- 1958
- Tongue
- English
- Weight
- 645 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0002-7863
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## Abstract For Abstract see ChemInform Abstract in Full Text.
N.M.R. spectra were obtained with Varian Associates HA-66 and Perkin-Elmer-R-12A spectrometers using MS as internal standard. Specific rotations were determined in CHC13 solution on a Perkin-Elmer model 141 polarimeter.
Acetylene-containing amino acids, obtained in enantiopure form via an enzymatic resolution process, serve as versatile intermediates in the synthesis of various highly functionalized heterocycles. The key transformations, intramolecular OC-and NC-bond formation, proceed via Pd-catalysis.