𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Syntheses of Tricyclic Analogues of O6-Methylguanine.

✍ Scribed by David M. Hammond; Dolores Edmont; Ana R. Hornillo-Araujo; David M. Williams


Publisher
John Wiley and Sons
Year
2004
Weight
92 KB
Volume
35
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


πŸ“œ SIMILAR VOLUMES


ChemInform Abstract: The Synthesis and P
✍ Ana R. Hornillo-Araujo; Adam J. M. Burrell; Miren K. Aiertza; Takayuki Shibata; πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons βš– 15 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

Differential inactivation of O6-methylgu
✍ Katsuyoshi Mineura; Masahito Fukuchi; Masayoshi Kowada; Isamu Terashima; Kohfuku πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 French βš– 473 KB

Activity of 06-methylguanine-DNA methyltransferase (MGMT) is well related with drug resistance of tumor cells to chloroethylnitrosoureas (CENUs), because MGMT removes CENU-induced O6-alkyIguanines in DNA by accepting the alkyl group at a cysteine moiety. Inactivation of MGMT is a feasible way to ove

Inactivation of O6-methylguanine-DNA met
✍ Jost Reinhard; Uta Eichhorn; Manfred Wiessler; Bernd Kaina πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 150 KB

The DNA-repair protein O 6 -methylguanine-DNA methyltransferase (MGMT) is a decisive determinant of resistance of tumor cells to methylating and chloroethylating anti-cancer drugs. Therefore, selective inhibition of MGMT in tumors is expected to cause tumor sensitization. Several inhibitors of MGMT

Formation and repair of O6-methylguanine
✍ Pawel Baranczewski; Peter Nehls; Rigomar Rieger; Uta Pich; Manfred F. Rajewsky; πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 96 KB

Mutagen-induced chromatid aberrations are not DNA as well as in FokI sequences of the field bean randomly distributed along the metaphase chromo-after exposure to MNU. In either case, similar numsomes. In the field bean (Vicia faba), defined late-bers of adducts per nucleotide were found immedirepli