The Supramolecular Helical Architecture of 8-Oxoinosine and 8-Oxoguanosine Derivatives
✍ Scribed by Stefano Lena; Mauro A. Cremonini; Francesco Federiconi; Giovanni Gottarelli; Carla Graziano; Luca Laghi; Paolo Mariani; Stefano Masiero; Silvia Pieraccini; Gian Piero Spada
- Book ID
- 101836146
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 498 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0947-6539
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📜 SIMILAR VOLUMES
In model studies directed to the total synthesis of guanofosfocins, a unique glycosydic bond formation between the 8-oxoinosine derivatives and mannopyranosyl donor is described. The reaction employing previously reported conditions resulted in the formation of two regioisomers, the 8-O-and N7-manno
## Abstract ^13^C NMR spectra of two C‐8‐oxo purine nucleosides, 8‐oxoguanosine and 8‐oxoadenosine, were recorded as a function of pH. The pH dependence of ^13^C chemical shifts and ^13^C‐^1^H coupling constants associated with the purine carbon resonances was analyzed to probe the sites and extent