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The suprachiasmatic nucleus functions beyond circadian rhythm generation

โœ Scribed by K. Hu; F.A.J.L. Scheer; P.Ch. Ivanov; R.M. Buijs; S.A. Shea


Book ID
116788158
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
411 KB
Volume
149
Category
Article
ISSN
0306-4522

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Metabolic activity in the suprachiasmatic nucleus (SCN), a center of biological rhythm, is higher during the daytime than at night. The rhythmic oscillation in the SCN is feedback controlled by the CLOCK/BMAL1 heterodimer binding to the E-box in target genes (e.g., Argvasopressin). Similar transcrip