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Gene expression in suprachiasmatic nucleus and circadian rhythms

โœ Scribed by Ognian Christov Ikonomov; Alexander Gueorgiev Stoynev


Book ID
107899653
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
968 KB
Volume
18
Category
Article
ISSN
0149-7634

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Metabolic activity in the suprachiasmatic nucleus (SCN), a center of biological rhythm, is higher during the daytime than at night. The rhythmic oscillation in the SCN is feedback controlled by the CLOCK/BMAL1 heterodimer binding to the E-box in target genes (e.g., Argvasopressin). Similar transcrip