We have sequenced the mitochondrial-encoded NADH dehydrogenase subunit 6 gene from 19 species of birds. Comparison of the derived amino-acid sequences in 22 avian species, six mammals, and two fishes, reveals an intragenic rearrangement in mammals. The C-terminal half of the mammalian protein includ
The subunit I of the respiratory-chain NADH dehydrogenase fromCephalosporium acremonium: the evolution of a mitochondrial gene
✍ Scribed by Miguel A. Peñalva; Jose L. Garcia
- Publisher
- Springer-Verlag
- Year
- 1986
- Tongue
- English
- Weight
- 389 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0172-8083
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✦ Synopsis
A Cephalosporium acremonium mitochondrial gene equivalent to human URF1 has been identified. The primary structure of the protein is highly homologous to its human (39%) and A. nidulans (66%) counterparts. Hydrophobicity profiles and predicted secondary structures are also very similar suggesting that this gene codes for the subunit I of the respiratorychain NADH dehydrogenase. The nucleotide sequence of the gene, 70% homologous to the A. nidulans one, presents a high AT content (72%) and this fact is reflected in the codon usage.
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