Molecular characterization and mutational analysis of the human B17 subunit of the mitochondrial respiratory chain complex I
β Scribed by J. Smeitink; J. Loeffen; Roel Smeets; Ralf Triepels; W. Ruitenbeek; Frans Trijbels; L. van den Heuvel
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 150 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Respiratory chain enzymes were studied in isolated mitochondria of two patients with mitochondrial myopathy. Both patients had been suffering from chronic progressive external ophthalmoplegia and abnormal muscular fatigability since late childhood. One of the patients exhibited the complete triad of
## Abstract A new parameter is presented for considering the contribution from each complex of the mitochondrial respiratory chain to the creation of the electrochemical gradient. This parameter is the proton gradient generated in each complex per pair of electrons transported (ΞH^+^/2e^β^) and may