The structure of the capsular polysaccharide obtained from a new serogroup (L) of Neisseria meningitidis
β Scribed by Harold J. Jennings; Czeslaw W. Lugowski; Fraser E. Ashton; J.Alan Ryan
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 456 KB
- Volume
- 112
- Category
- Article
- ISSN
- 0008-6215
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β¦ Synopsis
A newly isolated serogroup of Neisseria meningitidis (serogroup L), obtained from contacts of a patient with meningococcal meningitis, elaborates a structurally unique, capsular polysaccharide. The polysaccharide contains only 2-acetamido-2-deoxy-D-glucosyl and phosphate constituents in the molar ratio of 3:1, and is composed of the following repeating unit.
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The main structure of a lipopolysaccharide R-type core oligosaccharide common to a number of different strains of Neisseria meningitidis has been elucidated. Methylation analysis, specific degradations, and nuclear magnetic resonance spectroscopic analysis of the dephosphorylated cores indicated tha
We investigated the population genetics in collections of meningococci sampled in Cuba during the period 1983-2005, thereby covering a period before and after the introduction of an antimeningococcal B-C vaccine. A total of 163 case isolates and 210 isolates from healthy carriers were characterized
Capsular polysaccharide (CPS) was obtained by water-saline extraction of the Alteromonas sp. CMM 155. On the basis of solvolysis with anhydrous HF and 1H-and 13C-NMR spectral data, including NOE experiments, it was concluded that the capsular polysaccharide had the following structure containing nov