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The structure of an R-type oligosaccharide core obtained from some lipopolysaccharides of Neisseria meningitidis

✍ Scribed by Harold J. Jenning; Kenneth G. Johnson; Lennart Kenne


Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
500 KB
Volume
121
Category
Article
ISSN
0008-6215

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✦ Synopsis


The main structure of a lipopolysaccharide R-type core oligosaccharide common to a number of different strains of Neisseria meningitidis has been elucidated. Methylation analysis, specific degradations, and nuclear magnetic resonance spectroscopic analysis of the dephosphorylated cores indicated that they all have the following structure. (formula see text) The determinants responsible for the L3, L7, and L9 meningococcal lipopolysaccharide serotypes are situated in this oligosaccharide.