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The Structure of Nucleic Acids and Their Role in Protein Systheis


Publisher
Elsevier
Year
1957
Weight
112 KB
Volume
46
Category
Article
ISSN
0095-9553

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๐Ÿ“œ SIMILAR VOLUMES


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## Abstract Statistical analysis of structures from the PBD has been used to examine the role that the aromatic amino acids play in proteinโ€“nucleic acid recognition. In proteinโ€“DNA complexes, the residues Phe and His are found to bind selectively to the DNA chainโ€”Phe to A and T, and His to T and G.

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## Abstract __Intercalating nucleic acids (INAยฎs) with insertions of (__R__)โ€1โ€__O__โ€(1โ€pyrenylmethyl)glycerol were hybridized with locked nucleic acids (LNAs). INA/LNA duplexes were found to be less stable than the corresponding DNA/LNA duplexes when the INA monomer was inserted as a bulge close t