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The structure of glutamine-binding protein complexed with glutamine at 1.94 Å resolution: comparisons with other amino acid binding proteins

✍ Scribed by Yuh-Ju Sun; John Rose; Bi-Cheng Wang; Chwan-Deng Hsiao

Book ID: 115628474
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 415 KB
Volume: 278
Category: Article
ISSN: 0022-2836
DOI: 10.1006/jmbi.1998.1675

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## Abstract A novel ligand‐binding site with functional implications has been identified in phospholipase A~2~ (PLA~2~). The binding of non‐steroidal anti‐inflammatory agent indomethacin at this site blocks both catalytic and anti‐coagulant actions of PLA~2~. A group IIA PLA~2~ has been isolated fr