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The structure of aureo-alcohol, a novel degradation product of aureothin

✍ Scribed by Hisao Nakata; Yoshimasa Hirata

Publisher: Elsevier Science
Year: 1965
Tongue: French
Weight: 186 KB
Volume: 6
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)90224-7

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✦ Synopsis

During the course of the structure elucidation atudlee of aureothin (I)(l), we have carried out the alkaline hydrogen peroxide'oxidation reaction, and obtalned aureothlnic acid (II) and aureothinic ketone (III) aa two major oxidation products (2).

A careful fractionation of the residual reaction mixture further afforded a small amount of a new degradation product, aureo-alcohol (IV), the properties of which ere very peculiar and in marked contrast to those of II or III. The present paper deaoribee the structural assignment of this compound mainly from spectroscopic evidencea.

Aureo-alcohol (Iv), m.p. 108 -109*, ie en optically Inactive, neutral substance and is relatively stable to acid8 and baeee.

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