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The structure of Arteannuin B and its Acid Hydrolysis Product

✍ Scribed by David G. Leppard; Max Rey; André S. Dreiding; Rita Grieb


Publisher
John Wiley and Sons
Year
1974
Tongue
German
Weight
684 KB
Volume
57
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Die Struktur des Sesquiterpen‐γ‐Laktons Arteannuin B (1) wurde röntgenographisch und diejenige seines Hydrolyseproduktes (2) durch eine vollständige Analyse des NMR.‐Spektrums ermittelt.


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## Abstract The two isomeric monocarbamates, 2b and 2c, related to the antitumor drug carmethizole (1) were synthesized and the structure of the carmethizole hydrolysis product, 2b, was established by X‐ray crystallography. The chemical reactivity, toxicity, and antitumor activity of the two monoca