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The structural gene for the mitochondrial aldehyde dehydrogenase maps to human chromosome 12

✍ Scribed by T. Braun; K. H. Grzeschik; E. Bober; S. Singh; D. P. Agarwal; H. W. Goedde

Publisher: Springer
Year: 1986
Tongue: English
Weight: 527 KB
Volume: 73
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00279102

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✦ Synopsis

A cloned 850 bp cDNA fragment corresponding to the 3'-coding part of human ALDHI-mRNA was used as a probe for the chromosomal assignment of the ALDHI gene. Southern blot analysis of human-rodent somatic cell hybrids indicates that the human ALDHI gene resides on chromosome 12.

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