𝔖 Bobbio Scriptorium
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The stoichiometry of J chain in human secretory dimeric IgA

✍ Scribed by J. Zikan; J. Mestecky; R. Kulhavy; J.C. Bennett

Book ID
119089616
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
382 KB
Volume
23
Category
Article
ISSN
0161-5890

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Mucosal J (joining) chain-expressing IgA immunocytes produce dimeric IgA that is actively transported by the epithelial polymeric Ig receptor (pIgR) to exocrine secretions. Release of secretory IgA (SIgA) occurs by cleavage of the covalently linked pIgR ectodomain, also known as bound secretory comp