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The carbohydrate composition of J chain from human serum and secretory IgA

✍ Scribed by William Niedermeier; Milan Tomana; Jiri Mestecky


Book ID
115749358
Publisher
Elsevier Science
Year
1972
Weight
204 KB
Volume
257
Category
Article
ISSN
0005-2795

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Mucosal J (joining) chain-expressing IgA immunocytes produce dimeric IgA that is actively transported by the epithelial polymeric Ig receptor (pIgR) to exocrine secretions. Release of secretory IgA (SIgA) occurs by cleavage of the covalently linked pIgR ectodomain, also known as bound secretory comp