The stiff man and stiff man plus syndromes
β Scribed by P. Brown; C. D. Marsden
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 42 KB
- Volume
- 246
- Category
- Article
- ISSN
- 0340-5354
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π SIMILAR VOLUMES
## Abstract A second large family with a dominantly inherited benign disorder resembling the stiffβman syndrome is reported. The infants are markedly hypertonic at birth, but their tone becomes almost normal by 3 years of age. Stiffness reappears at adolescence, often precipitated by sudden movemen
## Abstract The stiff man syndrome (SMS) and its variants, focal SMS, stiff limb (or leg) syndrome (SLS), jerking SMS, and progressive encephalomyelitis with rigidity and myoclonus (PERM), appear to occur more frequently than hitherto thought. A characteristic ensemble of symptoms and signs allows
broadens the considerable clinical heterogeneity of movement disorders reported in late-onset HD. tromyographic pattern of continuous muscle activity at rest in the affected muscles. Muscle spasms and axial stiffness usually improve with diazepam or baclofen.' Since the initial description of SMS b