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The stereostructures of [1,1′-bicyclohexyl]-2,2′-diones: A reassignment

✍ Scribed by Scott E Denmark; Christopher J Cramer; Jeffrey A Sternberg

Book ID
104217971
Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
211 KB
Volume
27
Category
Article
ISSN
0040-4039

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The compound [2-(1-diethylaminopropyl)] 1-hydroxy-1,1Ј-bicyclohexyl-2-carboxylate 1 is a muscarinic antagonist characterized by the presence of three chiral atoms and eight possible stereoisomers. The binding affinities to the five cloned m 1 -m 5 muscarinic receptors of the stereoisomers of 1 were