The stereochemistry of hydrogen elimination in the biological conversion of 5α-cholest-8-en-3β-ol to 5α-cholest-7-en-3β-ol
✍ Scribed by L. Canonica; A. Fiecchi; M. Galli Kienle; A. Scala; G. Galli; E. Grossi Paoletti; R. Paoletti
- Book ID
- 119480983
- Publisher
- Elsevier Science
- Year
- 1968
- Tongue
- English
- Weight
- 150 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0039-128X
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The X-ray crystal structure of 3~-benzoyloxy-6a-chloro-5a-cholest-7-ene (IV) was determined by the heavy atom method and ref'med to R ---0.063 (space group P2s, a --11.364, b = 11.089, c --12.232,/~ = 99.43 °, Z ---2). IV was previously shown to be an important intermediate in the acid-catalyzed iso
Treatment of 3~.benzoyloxy-140, 15wepoxy-5(~.cholesg-7-ene with boron trifluoride-etherate 8ave, in 43% yield, 30-benzoyloxy-Sa, 14~cholest-7-en,15-one with the unnatt~ral C-D ring juncture, Reduction of the latteg compound with lithium aluminum hydride gave 15a, 14O-~holest-7.en'3p, 15wdiol and 5~,