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The stereochemistry of a nine-membered ring analogue of nefopam, a nonnarcotic analgesic drug

โœ Scribed by Robert Glaser; Dror Shiftan; Marc Drouin

Book ID
105519233
Publisher
Springer
Year
1995
Tongue
English
Weight
803 KB
Volume
6
Category
Article
ISSN
1040-0400

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โœ Robert Glaser ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 621 KB

The 'H NMR spectrum (CD,CI,) of the mesylate analogue of phendimetrazine bitartarate, a central nervous system stimulant and an anorexic drug, showed two isomers (ratio x 17: 1) differing in the stereochemistry of the N+HCH, moiety. A similar diastereomeric ratio was also noted in 13C{1H} NMR spectr