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The stereochemical course of intramolecular vinylogous Mannich reactions

โœ Scribed by Stephen F Martin; Scott K Bur


Book ID
104258185
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
204 KB
Volume
38
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES


Vinylogous Mannich reactions. Stereosele
โœ Stephen F. Martin; Scott K. Bur ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 669 KB

A concise synthesis of (-)-3, a known precursor of pumiliotoxin 251D, has been completed using a vinylogous Mannich reaction as a key construction. Silyloxyfuran 10 added to methoxypyrrolidine 20 in the presence of TMS-OTf to give a mixture (4.8:1) of 21 and 22 in 57% yield. Reduction and global dep

THE COURSE OF THE MANNICH REACTION1
โœ LIEBERMAN, S. V.; WAGNER, E. C. ๐Ÿ“‚ Article ๐Ÿ“… 1949 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 776 KB