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The sonic hedgehog pathway in chordoid tumours

โœ Scribed by Justin M M Cates; Doha M Itani; Cheryl M Coffin; Brian D Harfe


Book ID
108780906
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
341 KB
Volume
56
Category
Article
ISSN
0309-0167

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Genetic evidence that Sil is required fo
โœ Shai Izraeli; Linda A. Lowe; Virginia L. Bertness; Stefano Campaner; Heidi Hahn; ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 425 KB

## Abstract Summary: The __Sil__ gene encodes a cytosolic protein required for mouse embryonic midline and left/right axial development. Based on the phenotype of __Sil__ mutant embryos, we hypothesized that Sil may be required for the activity of Sonic Hedgehog (Shh), a secreted signaling molecule