The synthesis of peptide-oligonucleotide
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Suzanne Peyrottes; Béatrice Mestre; Fabienne Burlina; Michael J. Gait
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Article
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1998
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Elsevier Science
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French
⚖ 646 KB
Solid-phase synthesis of several peptide-oligonuclcotide conjugates has been achieved using a peptide fragment coupling strategy on a conlrolled pore glass support. The conjugates contain either a hydrophobic tetrapeptide LGIG or an 8-residue basic pcptide of the HIV-1 Tat protein coupled to one of