The Solution Structure of a Class II Major Histocompatibility Complex Superantigen Binding Domain
โ Scribed by Michael J. Jablonsky; Prem S. Subramaniam; Howard M. Johnson; Jeffry K. Russell; N.Rama Krishna
- Book ID
- 115580309
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 162 KB
- Volume
- 234
- Category
- Article
- ISSN
- 0006-291X
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## Abstract The activation of helper T cells by peptides bound to proteins of the class II Major Histocompatibility Complex (MHC II) is pivotal to the initiation of an immune response. The primary functional requirement imposed on MHC II proteins is the ability to efficiently bind thousands of diff
Streptococcal pyrogenic exotoxin A (SPEA) is an important pathogenicity factor of group A streptococci. It is a member of the family of ,,superantigens" produced by Staphylococcus aureus and Streptococcus pyogenes and its T lymphocyte stimulating activity is involved into the pathogenesis of certain