𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The significance of thermotolerance after 41°C hyperthermia: In vivo and in vitro tumor and normal tissue investigations

✍ Scribed by J.L. Meyer; I. Van Kersen; B. Becker; G.M. Hahn

Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
963 KB
Volume
11
Category
Article
ISSN
0360-3016

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Expression of feline type-C virus in nor
Expression of feline type-C virus in normal and tumor tissues of the domestic cat
✍ Reuven Levin; Sandra K. Ruscetti; Wade P. Parks; Edward M. Scolnick 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 967 KB

## Abstract Tumor and normal tissues from domestic cats were examined for FeLV and RD‐114 specific nucleic acids and proteins. Virus‐positive tissues showed a 100‐ to 200‐fold higher level of FeLV and a 200‐ to 400‐fold higher level of FeLV p30 than virus‐negative tumors and normal cat tissues. In

A proposal for the physiological signifi
A proposal for the physiological significance of mdr1 and Bcrp1/Abcg2 gene expression in normal tissue regeneration and after cancer therapy
✍ David Israeli; Simin Ziaei; Patrick Gonin; Luis Garcia 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 192 KB

Cellular multi-drug resistance (MDR), which often develops in cancer cells of patients subjected to anti-cancer treatment, remains a significant barrier to successful cancer therapy. One of the principal causes of cellular MDR development is an increased expression of ABC-transporter genes such as m

A derivative of staurosporine (CGP 41 25
A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and In vitro anti-proliferative as well as In vivo anti-tumor activity
✍ Thomas Meyer; Urs Regenass; Doriano Fabbro; Enrica Alteri; Johannes Röusel; Marc 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 French ⚖ 632 KB

Analogues of staurosporine were synthesized and their ability to inhibit protein kinases was examined. Staurosporine is a potent but non-selective inhibitor of in vitro protein kinase C (PKC) activity (K5, 6.0 nn). The derivative CGP 41 25 I had reduced PKC activity with an IC,, of 50 nn but showed