The significance of prohibitin and c-Met/hepatocyte growth factor receptor in the progression of cervical adenocarcinoma
β Scribed by Hung-Wen Tsai; Nan-Haw Chow; Chao-Po Lin; Shih-Huang Chan; Cheng-Yang Chou; Chung-Liang Ho
- Book ID
- 116534089
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 254 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1532-8392
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## Abstract The receptor for the hepatocyte growth factor/scatter factor (HGF/SF), cβMet, plays a role in tumour promotion, progression and metastasis. In this study, we analysed chemically induced hepatocarcinogenesis in mice lacking a functional HGF receptor in their liver. Control and cβMet defi
mal and malignant epithelial cells and several other cell The c-met proto-oncogene encodes the tyrosine kinase types, including endothelial cells and melanocytes. 4,5 receptor for hepatocyte growth factor (HGF), a potent It has been reported that the expression of c-Met is enmitogen and motogen for