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The signals and pathways activating cellular senescence

✍ Scribed by Ittai Ben-Porath; Robert A. Weinberg

Book ID
116306902
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
373 KB
Volume
37
Category
Article
ISSN
1357-2725

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## Abstract **Background:** Cellular senescence is a state of irreversible growth arrest shown by normal cells, and has been most extensively studied in replicative senescence caused by telomere shortening. Several conditions, including oncogenic Ras over‐expression and inappropriate culture condit