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Activation of nuclear factor-kappa B signalling promotes cellular senescence

✍ Scribed by Rovillain, E; Mansfield, L; Caetano, C; Alvarez-Fernandez, M; Caballero, O L; Medema, R H; Hummerich, H; Jat, P S

Book ID
109972724
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
950 KB
Volume
30
Category
Article
ISSN
0950-9232

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Nuclear factor kappa B (NF-B)/rel is the family of ubiquitous transcriptional activators involved in regulation of diverse immune and inflammatory responses. It also plays a role in control of cell growth and apoptosis. In its inactive form NF-B remains in the cytoplasm sequestered through interacti