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The Signaling Pathways of Erythropoietin and Interferon-γ Differ in Preventing the Apoptosis of Mature Erythroid Progenitor Cells

✍ Scribed by Kittiphong Paiboonsukwong; Ilseung Choi; Takamitsu Matsushima; Yasunobu Abe; Junji Nishimura; Pranee Winichagoon; Suthat Fucharoen; Hajime Nawata; Koichiro Muta

Book ID
105675967
Publisher
Carden Jennings Publishing
Year
2003
Tongue
English
Weight
417 KB
Volume
78
Category
Article
ISSN
0925-5710

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## Abstract ## Objective Both type I interferons (IFNα and IFNβ) and type II IFN (IFNγ) signal via pSTAT‐1. Immunohistochemistry and the gene expression signatures of rheumatoid arthritis (RA) synovial tissue suggest an activated IFN/STAT‐1 signaling pathway. The aim of this study was to determine