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The serum pharmacokinetics of digoxin as an immunogen and hapten in the rabbit

✍ Scribed by Nina M. Griffiths; David S. Hewick; Ian H. Stevenson

Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
432 KB
Volume
7
Category
Article
ISSN
0192-0561

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The effect of itraconazole (ITZ) on the pharmacokinetics of digoxin (DGX) was investigated in guinea pigs. The plasma concentrations of DGX in guinea pigs following treatment with ITZ (20 mg/kg intraperitoneally (i.p.)) after intravenous (i.v.) administration of DGX (0.125 mg/kg) were significantly