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The SERPINE2 Gene Is Associated with Chronic Obstructive Pulmonary Disease

✍ Scribed by Dawn L. DeMeo; Thomas J. Mariani; Christoph Lange; Sorachai Srisuma; Augusto A. Litonjua; Juan C. Celedón; Stephen L. Lake; John J. Reilly; Harold A. Chapman; Brigham H. Mecham; Kathleen J. Haley; Jody S. Sylvia; David Sparrow; Avrum E. Spira; Jennifer Beane; Victor Pinto-Plata; Frank E. Speizer; Steven D. Shapiro; Scott T. Weiss; Edwin K. Silverman


Book ID
117854737
Publisher
American Society of Human Genetics
Year
2006
Tongue
English
Weight
525 KB
Volume
78
Category
Article
ISSN
0002-9297

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## Abstract Chronic obstructive pulmonary disease (COPD) is a multifactorial disorder characterized by irreversible airflow obstruction due to chronic inflammation. Hence, the gene encoding the anti‐inflammatory cytokine IL 11 is a good candidate for being involved in the genetic predisposition to