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The Sequential Enzyme-catalyzed Esterification of a prochiral dicarboxylic anhydride – an improved access to 1-(2-methylpropyl) 5-hydrogen (2R,4S)-2,4-dimethylpentanedioate

✍ Scribed by Dr. R. Ozegowski; A. Kunath; H. Schick


Book ID
105354420
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
264 KB
Volume
336
Category
Article
ISSN
1615-4150

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📜 SIMILAR VOLUMES


Enzymes in organic synthesis, 25. Lipase
✍ Ozegowski, Rüdiger ;Kunath, Annamarie ;Schick, Hans 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 462 KB 👁 1 views

## Abstract The preparation of enantiomerically pure 1‐(2‐methylpropyl) 4‐hydrogen (__S__)‐2‐methylbutanedioate (__ent__‐3) by an enzyme‐catalyzed sequential esterification of (±)‐2‐methylbutanedioic anhydride (__rac__‐1) demands two different enzymes. Lipozyme, a lipase from __Mucor miehei__, was