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ChemInform Abstract: Enzymes in Organic Synthesis. Part 25. Lipase-Catalyzed Sequential Esterification of (.+-.)-2-Methylbutanedioic Anhydride - A Biocatalytical Access to an Enantiomerically Pure 1-Monoester of (S)-2- Methylbutanedioic Acid.

✍ Scribed by R. OZEGOWSKI; A. KUNATH; H. SCHICK


Book ID
112023690
Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
26
Category
Article
ISSN
0931-7597

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Enzymes in organic synthesis, 25. Lipase
✍ Ozegowski, Rüdiger ;Kunath, Annamarie ;Schick, Hans 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 462 KB 👁 1 views

## Abstract The preparation of enantiomerically pure 1‐(2‐methylpropyl) 4‐hydrogen (__S__)‐2‐methylbutanedioate (__ent__‐3) by an enzyme‐catalyzed sequential esterification of (±)‐2‐methylbutanedioic anhydride (__rac__‐1) demands two different enzymes. Lipozyme, a lipase from __Mucor miehei__, was