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The selective degradation of pyrimidines in nucleic acids by permanganate oxidation

✍ Scribed by H. Hayatsu; T. Ukita


Book ID
118850320
Publisher
Elsevier Science
Year
1967
Tongue
English
Weight
323 KB
Volume
29
Category
Article
ISSN
0006-291X

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Studies on the chemical modifications of
✍ Hikoya Hayatsu; Shigeru Iida πŸ“‚ Article πŸ“… 1969 πŸ› Elsevier Science 🌐 French βš– 257 KB

In our previous communication, we have reported that pyrimidine residues, especially thymine residues, in nucleic acids can be selectively oxidized with permanganate under mild reaction conditions of pH 6. 7 and 0' (I). This new method of chemical modification of nucleic acids is potentially useful