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The search for low-penetrance cancer susceptibility alleles

✍ Scribed by Houlston, Richard S; Peto, Julian


Book ID
110069019
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
156 KB
Volume
23
Category
Article
ISSN
0950-9232

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## Dear Sir, A positive family history is one of the most firmly established risk factors for breast cancer (BC). Women with at least one firstdegree relative with BC have an 1.8-fold risk to develop this disease themselves. 1 Several genes have been found to cause BC susceptibility, most notably