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The Search for Folding Intermediates and the Mechanism of Protein Folding

✍ Scribed by Baldwin, Robert L.

Book ID: 121430689
Publisher: Annual Reviews
Year: 2008
Tongue: English
Weight: 352 KB
Volume: 37
Category: Article
ISSN: 1936-122X
DOI: 10.1146/annurev.biophys.37.032807.125948

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## Abstract The first stage of protein self‐organization—the formation of a fluctuating secondary structure in the unfolded protein chain—is considered. The stereochemical theory is presented enabling one to calculate helix‐coil and β‐structure‐coil equilibrium constants. It is shown that the most