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The search for disease susceptibility genes. Medical and ethical problems of predictive medicine

✍ Scribed by Jean-Pierre Revillard


Book ID
117578107
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
126 KB
Volume
322
Category
Article
ISSN
0764-4469

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For diseases with complex genetic etiology, more than one susceptibility gene may exist in a single chromosomal region. Under explicit assumptions about the number of disease genes in a region, generalized estimating equations (GEE) can be used to estimate the putative disease gene location(s) and e